Multivalency ensures persistence of a +TIP body at specialized microtubule ends
Sandro M. Meier, Ana-Maria Farcas, Anil Kumar, Mahdiye Ijavi, Robert T. Bill, Jörg Stelling, Eric Dufresne, Michel O. Steinmetz, Yves Barral. Nature Cell Biology (2023) 25, 56-67.
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The clever glue keeping the cell's moving parts connected
Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue. Clinging to the ends of filaments called microtubules, the glue they discovered ensures the nucleus is correctly positioned for cell division.