Demixing the cell: how cells channel and store signaling information
Yves Barral, member and spokesperson of BML, is a co-Editor of the April themed Issue of Current Opinion in Cell Biology on "Cell Signalling".
Yves Barral, member and spokesperson of BML, is the Editor, together with Angel R. Nebreda from ICREA and Institute for Research in Biomedicine, Barcelona, of the April themed Issue of Current Opinion in Cell Biology on "Cell Signalling" where several authors explore the role of liquid-liquid phase separation in the organization and dynamics of the eukaryotic cell. Using the Editors own words: “Collectively, these reviews depict a field in transformation, where important concepts such as phase separation and its capability to modulate the reception, propagation, and storage of information, as well as other memory mechanisms, such as chromatin states, are changing our understanding of how cells perceive and respond to their environment. Globally, the emerging picture reveals astoundingly ‘fluid’ signaling mechanisms that start to account for the not less amazing ability of cells to integrate complex information in highly plastic manners and mount very customized responses that are pertinently adapted to their environment and specific functions.”